TABLE 3.
Total Median Concentrations of Iron, Manganese, and Zinc Measured in the Cerebellum, the Cerebrum, the Brain Stem, and the Olfactory Bulb With Inductively Coupled Mass Spectrometry for All Groups Separately
| Element Neuroanatomical Region | Saline I (1 wk PI) | Saline II (26 wk PI) | Saline III (52 wk PI) | Gadobutrol (52 wk PI) | Gadodiamide (52 wk PI) | |
|---|---|---|---|---|---|---|
| Zn | Cerebellum | 318 (304–341) | 411 (410–421) | (26 weeks PI) | 479 (473–479) | 462 (459–521) |
| Cerebrum | 265 (255–270) | 356 (323–358) | 343 (329–344) | 328 (327–364) | 344 (333–361) | |
| Brain stem | 286 (246–291) | 313 (287–316) | 318 (295–327) | 307 (278–324) | 307 (279–315) | |
| Olfactory bulb | 442 (394–449) | 500 (500–539) | 617 (616–626) | 612 (576–623) | 629 (626–631) | |
| Mn | Cerebellum | 8.4 (8.1–8.4) | 9.1 (8.1–10.4) | 9.0 (8.8–9.1) | 9.4 (9.4–9.5) | 8.7 (8.7–9.37) |
| Cerebrum | 7.1 (7.1–7.7) | 9.1 (8.5–9.1) | 8.3 (8.2–8.6) | 8.6 (8.3–8.6) | 8.3 (7.8–8.4) | |
| Brain stem | 9.4 (8.7–10.3) | 8.7 (8.0–9.2) | 8.9 (8.7–8.9) | 9.3 (8.8–9.4) | 8.6 (8.3–9.4) | |
| Olfactory bulb | 8.2 (7.9–8.6) | 8.7 (8.1–9.4) | 9.4 (9.3–9.5) | 10.1 (9.5–10.1) | 8.6 (8.4–8.9) | |
| Fe | Cerebellum | 158 (156–159) | 140 (13–142) | 139 (138–149) | 144 (141–144) | 148 (148–149) |
| Cerebrum | 184 (180–195) | 190 (169–194) | 170 (169–176) | 172 (169–173) | 175 (174–179) | |
| Brain stem | 115 (112–143) | 102 (95–106) | 97 (94–99) | 95 (95–96) | 95 (93–96) | |
| Olfactory bulb | 193 (169–197) | 166 (162–174) | 179 (175–193) | 166 (161–188) | 170 (155–170) | |
Interquartile ranges are shown in round brackets.