TABLE 2.
Placebo |
VSL#3 |
|||||||
Baseline |
3 months |
Baseline |
3 months |
|||||
Total number | 30 |
30 |
30 |
30 |
||||
Sex | Males | Females | Males | Females | Males | Females | Males | Females |
AST (IU/l) | 51.2 ± 9.1 | 53.9 ± 10.3 | 49.7 ± 8.9 | 52.8 ± 9.5 | 53.4 ± 10.1 | 52.7 ± 9.4 | 46.5 ± 8.8*^ | 44.4 ± 7.6*^ |
ALT (IU/l) | 60.1 ± 15.1 | 56.7 ± 14.0 | 57.8 ± 14.4 | 57.2 ± 14.1 | 59.2 ± 15.0 | 58.3 ± 14.9 | 48.3 ± 10.1*^ | 52.7 ± 11.8*^ |
AST/ALT | 0.85 ± 0.05 | 0.95 ± 0.08 | 0.86 ± 0.05 | 0.92 ± 0.07 | 0.90 ± 0.06 | 0.90 ± 0.06 | 0.96 ± 0.05*^ | 0.84 ± 0.04*^ |
γ-GT (IU/l) | 36.1 ± 7.0 | 36.9 ± 7.7 | 35.4 ± 6.8 | 35.1 ± 6.6 | 35.8 ± 6.8 | 35.9 ± 6.9 | 28.2 ± 5.9*^ | 29.4 ± 6.0*^ |
HIS | 33.9 ± 2.0 | 34.2 ± 2.2 | 34.9 ± 2.4 | 35.3 ± 2.6 | 35.1 ± 2.5 | 35.6 ± 2.7 | 34.1 ± 2.1*^ | 34.7 ± 2.3*^ |
Data are expressed as mean ± SDs. *p < 0.05 vs. baseline; ^p < 0.05 vs. placebo. AST, alanine aminotransferase; AST, aspartate aminotransferase; γ-GT, gamma-glutamyltransferase; HSI, hepatic steatosis index.