Figure 2.

CA alleviates pathological alterations in DSS-induced colitis. Colitis was induced as described in Figure 1 and colon samples were collected on day 10. (A) Histological analysis of colonic sections. Representative images of H-E-stained colonic sections of each group. (B) Total histological scores were the sum of all sub-scores shown in (C). (C) Colonic sections were scored on a scale of 0–4 based on the percentage of colon involvement by inflammation, percentage of crypt loss, presence of lymphoid follicles, edema, erosions, and density of infiltrating inflammatory cells. Data are presented as mean ± SD. Representative data of three independent experiments are shown. One-way analysis of variance (ANOVA) followed by Tukey's multiple comparisons test, *p < 0.05, **p < 0.01, and ***p < 0.001.