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Control paradigms with conditions of stranger mice. (A) Partner-Observing-Stranger-Pair-Housed (ParObsStrPH) mice were pair-housed with strangers after exposure to witnessing stress and identified the isolation effect in the behavioral paradigm. (B) Stranger Observing Isolated (StrObsIso) mice had witnessing experience of defeat that happened to strangers, rather than to their pair-housed partners, and identified the relationship effect in the behavioral paradigm.
