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. 2022 May 24;16:854486. doi: 10.3389/fnbeh.2022.854486

FIGURE 2.

FIGURE 2

Brain-wide microstructural changes measured by DTI fractional anisotropy (A), mean diffusivity (B), axial diffusivity (C), and radial diffusivity (D). Po, ParObsIso mice; Nsi, xScenIso mice; -log(p), statistical significance through Tukey’s range test; A, anterior; P, posterior; D, dorsal; V, ventral; L, left; R, right; lOC, lateral orbital cortex; SInh, non-homunculus region of the primary sensory cortex; SIfl, forelimb region of the primary sensory cortex; SIjaw, jaw region of the primary sensory cortex; vACC, ventral region of the anterior cingulate cortex; CA2sr, stratum radiatum of the hippocampal cornu ammonis (CA) 2 area; RSC, the retrosplenial cortex; VI, the primary visual cortex; dlOC, dorsolateral orbital cortex; InC, the insular cortex; CoA, the cortical amygdalar nucleus; MeA, medial amygdalar nucleus; CA3sl, stratum lucidum of the hippocampal CA3 area; dlEC, dorsolateral entorhinal cortex; OP, olfactory peduncle; PLC, prelimbic cortex; mOC, medial orbital cortex; CL, claustrum; MS, medial septal complex; mPOA, medial preoptic area; CB, cingulum bundle; CA3sr, stratum radiatum of the hippocampal CA3 area; CA3sl, stratum lucidum of the hippocampal CA3 area;CA3so, stratum oriens of the hippocampal CA3 area; CA3ipl, inner pyramidal layer of the hippocampal CA3 area; CA3opl, outer pyramidal layer of the hippocampal CA3 area; vOC, ventral orbital cortex; ACal, anterior limb of the anterior commissure; CC, corpus callosum; CA1so, stratum oriens of the hippocampal CA1 area.