Table 1.

Schema of the data matrix used for regression models construction

Sample	INH + RIF	EMB + PYR	…	rpoB	katG	gyrA	…
1	R	R	…	1	1	1	…
2	R	S	…	1	0	0	…
…

This matrix has the phenotypic information for each tested drug codified as R (resistant) or S (suceptible). It has also genotypic information for the specified gene set codified as 1 (presence of nosynonymous mutations after the pN/pS > 1 cross-point) or 0 (absence of nosynonymous mutations after the pN/pS > 1 cross-point). EMB, ethambutol; INH, isoniazid; PYR, pyrazinamide; RIF, rifampicin.