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. Author manuscript; available in PMC: 2023 Jul 1.
Published in final edited form as: Psychoneuroendocrinology. 2022 Apr 21;141:105773. doi: 10.1016/j.psyneuen.2022.105773

Fig. 3.

Fig. 3.

Estradiol increases hippocampal MMP-9 enzyme activity. OVX female mice (n = 7/group) received bilateral DH infusion of vehicle (V) or E2 (5 μg/hemisphere) and DH tissue was collected 30 min later (A). E2 treatment did not affect levels of MMP-9 protein expression (B,C), but did increase levels of MMP-9 enzyme activity (D). (**p < 0.01) Error bars indicate mean ± SEM.