Table 5. Functional and behavioural mediators in the association between multimorbidity and depression (Women).
Mediators | Indirect effect | Direct effect | Total effect | Mediating % | ||||||
---|---|---|---|---|---|---|---|---|---|---|
OR | 95% CI | P-Value | OR | 95% CI | P-Value | OR | 95% CI | P-Value | ||
Functional health | ||||||||||
ADL disability | 1.07 | [1.06,1.08] | <0.001 | 1.27 | [1.17,1.38] | <0.001 | 1.36 | [1.25,1.48] | <0.001 | 21.90 |
IADL disability | 1.08 | [1.06,1.09] | <0.001 | 1.27 | [1.17,1.38] | <0.001 | 1.37 | [1.26,1.48] | <0.001 | 23.32 |
Poor sleep | 1.14 | [1.11,1.16] | <0.001 | 1.21 | [1.11,1.31] | <0.001 | 1.37 | [1.26,1.49] | <0.001 | 40.52 |
Pain | 1.03 | [1.02,1.04] | <0.001 | 1.32 | [1.22,1.43] | <0.001 | 1.36 | [1.26,1.48] | <0.001 | 9.96 |
SRH | 1.14 | [1.12,1.16] | <0.001 | 1.21 | [1.11,1.32] | <0.001 | 1.38 | [1.27,1.5] | <0.001 | 40.17 |
Behavioural health | ||||||||||
Currently smoking | 1.00 | [1,1] | 0.90 | 1.36 | [1.25,1.48] | <0.001 | 1.36 | [1.25,1.48] | <0.001 | NA |
Alcohol use | 1.00 | [1,1] | 0.18 | 1.36 | [1.25,1.47] | <0.001 | 1.36 | [1.25,1.48] | <0.001 | NA |
Physical inactivity | 1.02 | [1.01,1.02] | <0.001 | 1.38 | [1.27,1.49] | <0.001 | 1.40 | [1.30,1.52] | <0.001 | 5.17 |
Obesity | 1.00 | [0.98,1.01] | 0.59 | 1.38 | [1.27,1.5] | <0.001 | 1.38 | [1.26,1.5] | <0.001 | NA |
OR: Odds ratio; CI: Confidence Interval; SRH: Self-rated health; ADL: Activities of Daily Living; IADL: Instrumental activities of daily living. Models are adjusted for age, education, place of residence, marital status, caste, religion, and MPCE quintile.