Table 2.

Coefficients of the association between breast cancer diagnosis and changes in physical function between pre- and post-diagnosis

	Group (cases vs controls)	Period (Post vs Pre)	Group*Period
Objectively measured physical Function
Grip strength (kilograms)
Average grip strength	0.14	−1.43 ***	−0.18
Max grip strength	0.008	−1.45 ***	0.02
Timed chair stand (seconds)	0.002	0.77 ***	0.35
Gait speed/stride length
Regular gait speed (meters per second)	0.03**	−0.06 ***	−0.03 *
Rapid gait speed (meters per second)	0.04*	−0.07 ***	−0.05 *
Regular stride length (meters)	0.008	−0.02 ***	−0.01
Rapid stride length (meters)	0.01	−0.007	−0.02
Quadriceps strength (pounds)
Average quadriceps strength	2.43	−8.43 ***	−3.18 *
Peak quadriceps strength	2.29	−8.44 ***	−3.25 *

^*:P value <0.05;

^**p value <0.01;

^***p value <0.0001.

All the models were adjusted for age at diagnosis (in continuous years), education level (<12 years, 12 years, 13–16 years, 17 years or more), physical activity (measured in total calories per week expended in past year), alcohol consumption (measured in total number drinks over lifetime), smoking (measured in pack-years: never smoke, <10, 10–−<30, 30–<50, >=50), history of hypertension (yes, no), diabetes (yes, no) and body mass index.