Table 3.

Coefficients of physical function trajectories in relation to breast cancer diagnosis ^*

	Average grip strength (kilograms)		Rapid gait speed (meters per second)		Average quadriceps strength (pounds)
	Estimate	P-value	Estimate	P-value	Estimate	P-value
Group (cases vs controls)	0.40	0.28	0.01	0.65	4.76	0.05
Period (Post vs Pre)	−0.68	<0.0001	−0.02	0.04	0.08	0.95
Group*Period	−0.31	0.38	0.01	0.73	−6.90	0.04
Time (years)	−0.39	<0.0001	−0.02	<0.0001	−1.62	<0.0001
Group*Time	0.04	0.32	0.002	0.65	0.24	0.54
Period* Time	0.06	0.04	−0.002	0.56	−1.44	<0.0001
Group*Period*Time	−0.11	0.09	−0.01	0.04	1.54	0.07

^*All the models were adjusted for age at diagnosis (in continuous years), education level (<12 years, 12 years, 13–16 years, 17 years or more), physical activity (measured in total calories per week expended in past year), alcohol consumption (measured in total number drinks over lifetime), smoking (measured in pack-years: never smoke, <10, 10–−<30, 30–<50, >=50), history of hypertension (yes, no), diabetes (yes, no) and body mass index.