Appendix 1—table 2. Pearson correlation coefficients and significance of the correlation between t0 and k1, t0 and Fmax and k1 and Fmax for the accumulation in single E. coli of all the fluorescent antibiotic derivatives investigated (apart from vancomycin) in individual E. coli.
Data from Figure 1—figure supplement 13 were used for these statistical comparisons. ****: p-value<0.0001, ***: p-value <0.001, **: p-value<0.01, *: p-value<0.05, ns: not significant, p-value>0.05.
| Pearson correlation coefficients and significance | |||
|---|---|---|---|
| Antibiotics | t0 vs k1 | t0 vs Fmax | k1 vs Fmax |
| Polymyxin B | –0,51, **** | –0,54, **** | 0,56, **** |
| Octapeptin | –0,46, **** | –0,61, **** | 0,20, ns |
| Tachyplesin | –0,13, ns | –0,10, ns | –0,01, ns |
| Linezolid | 0.03, ns | –0,21, ** | 0,05, ns |
| Ciprofloxacin | –0,12, ns | –0,11, ns | 0,29, *** |
| Trimethoprim | 0,06, ns | –0,32, **** | 0,11, ns |
| Roxithromycin | –0,22, *** | –0,10, ns | 0,41, **** |
| All antibiotics | –0,40, **** | –0,27, **** | 0,65, **** |