Fig. 3.

The probability of action-potential failure depends on sonication magnitude. (A and B) Representative experiments demonstrating action-potential failure (red asterisks) with increased FUS intensity (A) or increased FUS duration (B). Traces are plotted sequentially; the top trace (trial 1) was evoked first, and the traces below were recorded consecutively afterward (interstimulus interval, 5 s). In A, two units are excited by FUS (Aβ and Aδ). Note that increased sonication energy results in action-potential failure of the Aβ unit but not the Aδ unit.