Table 1.

Order of magnitude estimates of the contributions of different nuclear and cytoplasmic components to the inward and outward pressures that are exerted on the nucleus of nonstriated muscle cells

Species/source of pressure	Chromatin polymer, Pa	Chromatin counterions, Pa	Cytoskeletal elasticity, Pa	Cytoplasmic proteins, Pa	Nucleoplasmic proteins, Pa
Human	30	300	500	8,000	8,000
Fission yeast	1.5	20	500	8,000	8,000

Order of magnitude estimates of the contributions of different nuclear and cytoplasmic components to the inward and outward pressures that are exerted on the nucleus of nonstriated muscle cells. In striated muscle cells, the cytoskeletal stress is directional and may exceed hundred of kilopascals during contraction, making it the dominant contribution in that case, which is outside of the scope of this paper.