Table 3.
Predictive power of biomarkers as prognosticator of mortality in ICU.
| Variable | AUC | 95% CI | Criterion associated with best sensitivity and specificity at Youden index | Sensitivity | Specificity | Significance level P (Area = 0.5) |
|---|---|---|---|---|---|---|
| Age (years) | 0.644 | 0.550 to 0.730 | >63 | 59,76% | 66,67% | 0.0112 |
| D-dimer (ng/ml) | 0.607 | 0.511 to 0.697 | >1132 | 77.5% | 47.06% | 0.0711 |
| IL-6 (pg/ml) | 0.694 | 0.602 to 0.775 | >17.7 | 73.17% | 62.86% | 0.0003 |
| IL-10 (pg/ml) | 0.592 | 0.464 to 0.711 | >24.28 | 23.26% | 100% | 0.1910 |
| IL-6/Lymphocytes | 0.695 | 0.602 to 0.778 | >28.4 | 66.67% | 66.67% | 0.0005 |
| IL-10/Lymphocytes | 0.628 | 0.495 to 0.749 | >35.62 | 25.64% | 100% | 0.0773 |
| CRP/IL-6 | 0.663 | 0.569 to 0.748 | ≤8.411 | 75.61% | 54.55% | 0.0023 |
| CRP/IL-10 | 0.548 | 0.416 to 0.676 | ≤24.239 | 76.92% | 36.36% | 0.5310 |
| IIL-6/IL-10 | 0.551 | 0.419 to 0.679 | >2.52 | 51.28% | 72.73% | 0.5063 |