Table 5.

Predictive power of biomarkers as prognosticator of mechanical ventilation in ICU.

Variable	AUC	95% CI	Criterion associated with best sensitivity and specificity at Youden index	Sensitivity	Specificity	Significance level P (Area = 0.5)
Age (years)	0.556	0.449 to 0.663	>61	66.15%	49.06%	0.3087
D-dimer (ng/ml)	0.612	0.517 to 0.702	>1132	79.37%	41.18%	0.0355
IL-6 (pg/ml)	0.582	0.487 to 0.672	>24	64.62%	55.77%	0.1277
IL-10 (pg/ml)	0.532	0.405 to 0.656	≤5.43	35%	84.62%	0.6592
IL-6/Lymphocytes	0.564	0.468 to 0.656	>32.43	64.06%	54%	0.2488
IL-10/Lymphocytes	0.705	0.599 to 0.796	≤2.033	50%	92.31%	0.0002
CRP/IL-6	0.561	0.466 to 0.654	≤6.88	69.23%	50%	0.2591
CRP/IL-10	0.540	0.408 to 0.668	>8.8138	66.67%	60%	0.6021
IL-6/IL-10	0.588	0.454 to 0.712	>0.272	94.44%	28%	0.2643