Table 2.
Harmonized dataset of univariate Mendelian randomization for the effect of omega-3 fatty acids on lung cancer.
SNP | EA exposure | Other allele exposure | EA outcome | Other allele outcome | Chromosome | Exposure | Outcome | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
β | SE | p | β | SE | p | ||||||
rs10184054 | G | C | G | C | 2 | -0.036 | 0.005 | 5.6E − 15 | 0.006 | 0.021 | 0.776 |
rs10455872 | G | A | G | A | 6 | -0.063 | 0.008 | 2.8E − 17 | -0.028 | 0.044 | 0.564 |
rs11242109 | T | G | T | G | 5 | 0.024 | 0.004 | 2.4E − 09 | 0.036 | 0.019 | 0.047 |
rs112875651 | A | G | A | G | 8 | -0.087 | 0.004 | 3.5E − 98 | 0.007 | 0.019 | 0.702 |
rs1132899 | C | T | C | T | 19 | 0.027 | 0.004 | 8.6E − 11 | -0.009 | 0.018 | 0.619 |
rs11563251 | T | C | T | C | 2 | 0.035 | 0.006 | 3.2E − 08 | 0.041 | 0.031 | 0.178 |
rs1167998 | A | C | A | C | 1 | 0.071 | 0.004 | 3.6E − 66 | -0.036 | 0.020 | 0.061 |
rs11681659 | T | C | T | C | 2 | -0.025 | 0.004 | 2E − 08 | -5E-04 | 0.020 | 0.981 |
rs117143374 | C | T | C | T | 21 | -0.037 | 0.006 | 2.2E − 10 | 0.059 | 0.028 | 0.028 |
rs117733303 | G | A | G | A | 6 | -0.116 | 0.015 | 1.4E − 15 | -0.138 | 0.057 | 0.048 |
rs12226389 | C | T | C | T | 11 | -0.051 | 0.005 | 1.1E − 22 | -0.045 | 0.026 | 0.099 |
rs1260326 | C | T | C | T | 2 | -0.082 | 0.004 | 8.4E − 88 | 0.004 | 0.018 | 0.841 |
rs13424225 | T | G | T | G | 2 | 0.022 | 0.004 | 2.2E − 08 | 0.011 | 0.018 | 0.571 |
rs139974673 | C | T | C | T | 15 | 0.118 | 0.013 | 2.3E − 21 | -0.1 | 0.047 | 0.068 |
rs143355652 | T | C | T | C | 11 | -0.154 | 0.020 | 9.4E − 14 | -0.047 | 0.084 | 0.628 |
rs1672811 | C | T | C | T | 16 | 0.025 | 0.005 | 3E − 08 | -0.016 | 0.020 | 0.431 |
rs174564 | G | A | G | A | 11 | -0.337 | 0.004 | 1E − 200 | -0.061 | 0.018 | 0.002 |
rs1800978 | G | C | G | C | 9 | -0.037 | 0.006 | 5.2E − 09 | 0.033 | 0.028 | 0.234 |
rs261290 | C | T | C | T | 15 | -0.114 | 0.004 | 4E − 161 | -0.005 | 0.019 | 0.778 |
rs3018731 | G | A | G | A | 11 | -0.035 | 0.005 | 2E − 14 | 0.008 | 0.025 | 0.744 |
rs34663616 | A | C | A | C | 15 | 0.036 | 0.006 | 4.4E − 10 | -0.044 | 0.028 | 0.143 |
rs35135293 | T | C | T | C | 2 | -0.021 | 0.004 | 3.9E − 08 | -0.005 | 0.018 | 0.773 |
rs4000713 | A | G | A | G | 7 | -0.029 | 0.004 | 1E − 11 | -0.019 | 0.019 | 0.349 |
rs58542926 | T | C | T | C | 19 | -0.172 | 0.008 | 1E − 113 | -0.038 | 0.033 | 0.288 |
rs6129624 | A | G | A | G | 20 | -0.026 | 0.004 | 5.1E − 10 | -0.023 | 0.019 | 0.243 |
rs62466318 | T | C | T | C | 7 | -0.072 | 0.005 | 1.2E − 45 | 0.059 | 0.025 | 0.015 |
rs629301 | T | G | T | G | 1 | 0.038 | 0.005 | 1.3E − 14 | 0.02 | 0.021 | 0.359 |
rs633695 | G | A | G | A | 15 | 0.084 | 0.004 | 9.1E − 80 | -0.013 | 0.019 | 0.526 |
rs6601924 | C | T | C | T | 10 | 0.035 | 0.006 | 8.5E − 10 | 0.006 | 0.025 | 0.829 |
rs6693447 | G | T | G | T | 1 | 0.023 | 0.004 | 4.8E − 09 | 0.041 | 0.019 | 0.033 |
rs673335 | C | T | C | T | 11 | -0.067 | 0.006 | 1.1E − 34 | 0.024 | 0.024 | 0.325 |
rs6882345 | A | G | A | G | 5 | 0.029 | 0.004 | 1.9E − 13 | -0.016 | 0.019 | 0.388 |
rs72789541 | A | T | A | T | 16 | -0.081 | 0.004 | 5.6E − 75 | -0.01 | 0.020 | 0.624 |
rs73109460 | A | G | A | G | 7 | -0.035 | 0.006 | 9.2E − 10 | 0.024 | 0.031 | 0.447 |
rs737338 | T | C | T | C | 19 | -0.073 | 0.011 | 3.5E − 11 | -0.024 | 0.040 | 0.576 |
rs77960347 | G | A | G | A | 18 | 0.162 | 0.018 | 7.2E − 22 | 0.070 | 0.085 | 0.413 |
rs7819706 | G | A | G | A | 8 | -0.040 | 0.006 | 1.8E − 10 | 3E-04 | 0.026 | 0.990 |
rs7924036 | T | G | T | G | 10 | 0.023 | 0.004 | 5.5E − 10 | -0.005 | 0.018 | 0.778 |
rs7970695 | A | G | A | G | 12 | -0.025 | 0.004 | 1.2E − 10 | -0.013 | 0.019 | 0.472 |
rs9304381 | T | C | T | C | 18 | 0.053 | 0.005 | 5.2E − 24 | -0.004 | 0.024 | 0.884 |
rs964184 | C | G | C | G | 11 | -0.117 | 0.006 | 8.9E − 87 | -0.037 | 0.026 | 0.155 |
rs9987289 | G | A | G | A | 8 | 0.057 | 0.007 | 3.2E − 16 | -0.04 | 0.032 | 0.199 |
SNP: single-nucleotide polymorphism; SE: standard error; EA: effect allele; β: effect value.