Table 3.
Associations of omega-3 fatty acids with lung cancer in Mendelian randomization analysis.
| MR | Heterogeneity | Pleiotropy | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Methods | nSNP | Beta | OR (95% CI) | p | Method | Cochran's Q | p | Egger-intercept (95% CI) | p |
| IVW | 42 | -0.106 | 0.899 (0.817, 0.990) | 0.03 | IVW | 69.8 | 0. 240 | 0.006 (-0.006, 0.018) | 0.293 |
| MR-Egger | 42 | -0.156 | 0.856 (0.750, 0.977) | 0.026 | |||||
| Weighted median | 42 | -0.175 | 0.899 (0.817, 0.990) | 0.001 | |||||
| Simple mode | 42 | -0.104 | 0.901 (-0.678, 1.199) | 0.478 | |||||
| Weighted mode | 42 | -0.152 | 0.859 (0.782, 0.944) | 0.003 | |||||
MR: Mendelian randomization; SNP: single-nucleotide polymorphism; nSNP: number of SNPs; OR: odds ratio; CI: confidence interval; IVW: inverse variance weighted.