Table 1.

Summary of association results in four phenotype categories

Phenotype category	Number of phenotypes	Brain regions (IDPs)	Phenotype/IDP associations used to derive voxel-wise maps in Fig. 4
Blood assays	33	All 16 subcortical regions, WMH IDPs	Mean corpuscular hemoglobin versus χ in right putamen (r = 0.16, –log10 (P) = 190.37)
Health outcomes	44	MS: thalamus, WMH IDPs; anemia: putamen, caudate, substantia nigra; diabetes: pallidum, substantia nigra, caudate, putamen	MS (self-reported) versus χ in WMH (r = −0.068, –log10 (P) = 36.67); anemia (ICD10) versus χ in left putamen (r = −0.048, –log10 (P) = 18.65); diabetes diagnosed by doctor versus χ in right pallidum (r = 0.047, –log10 (P) = 17.38)
Food and drink	22	Substantia nigra, pallidum, caudate, putamen, hippocampus	Tea intake versus χ in right substantia nigra (r = −0.069, –log10 (P) = 37.01)
Alcohol consumption	10	Putamen, caudate, thalamus	Frequency of consuming six or more units of alcohol versus χ in thalamus (r = −0.043, –log10 (P) = 9.94)

The Pearson correlation r and –log₁₀ (P) values provided are unadjusted and calculated from two-sided association analyses.