Supplementary Table 1. Multiple regression analyses on changes in maximal and mean intima-media thickness (IMT) and Achilles tendon thickness at 2 years of follow-up in relation to lipid and clinical parameters.

Parameter	Unit in change	Regression coefficient	Robust SE	P-value	Standardized regression coefficient＊
Maximal IMT (n = 306)
Sex	Male vs. female	0.192	0.080	0.02	0.153
Age	Per 10 years	0.001	0.032	0.98	0.002
LDL cholesterol†	Per 10 mg/dL	-0.011	0.010	0.26	-0.058
HDL cholesterol†	Per 10 mg/dL	0.009	0.033	0.78	0.013
CAD	(+) vs. (−)	-0.143	0.099	0.15	-0.100
Hypertension	(+) vs. (−)	0.001	0.088	0.99	0.001
Ever-smoking	(+) vs. (−)	0.001	0.091	0.99	0.001
Mean IMT (n = 281)
Sex	Male vs. female	-0.002	0.044	0.96	-0.004
Age	Per 10 years	0.009	0.014	0.52	0.044
LDL cholesterol†	Per 10 mg/dL	-0.003	0.005	0.57	-0.034
HDL cholesterol†	Per 10 mg/dL	-0.017	0.014	0.23	-0.048
CAD	(+) vs. (−)	0.011	0.049	0.83	0.015
Hypertension	(+) vs. (−)	0.017	0.045	0.71	0.027
Ever-smoking	(+) vs. (−)	-0.015	0.045	0.73	-0.024
Achilles tendon thickness (n = 187)
Sex	Male vs. female	0.118	0.299	0.69	0.034
Age	Per 10 years	0.035	0.100	0.72	0.029
LDL cholesterol†	Per 10 mg/dL	0.036	0.040	0.37	0.070
HDL cholesterol†	Per 10 mg/dL	0.166	0.125	0.19	0.078
CAD	(+) vs. (−)	0.238	0.406	0.56	0.062
Hypertension	(+) vs. (−)	0.372	0.332	0.26	0.100
Ever-smoking	(+) vs. (−)	0.061	0.322	0.85	0.016

^＊Regression coefficient divided by standard deviation of the parameter of study.

^†Change from baseline at 2 years of follow-up.