Supplementary Table 2. Multiple regression analyses on changes in maximal and mean intima-media thickness (IMT) and Achilles tendon thickness at 4 years of follow-up in relation to lipid and clinical parameters.

Parameter	Unit in change	Regression coefficient	Robust SE	P-value	Standardized regression coefficient＊
Maximal IMT (n = 174)
Sex	Male vs. female	0.193	0.113	0.09	0.140
Age	Per 10 years	0.034	0.042	0.42	0.070
LDL cholesterol†	Per 10 mg/dL	-0.035	0.020	0.08	-0.155
HDL cholesterol†	Per 10 mg/dL	-0.048	0.047	0.30	-0.064
CAD	(+) vs. (−)	-0.164	0.144	0.26	-0.110
Hypertension	(+) vs. (−)	0.066	0.135	0.63	0.045
Ever-smoking	(+) vs. (−)	-0.110	0.125	0.38	-0.075
Mean IMT (n = 161)
Sex	Male vs. female	0.017	0.076	0.83	0.024
Age	Per 10 years	0.049	0.020	0.02	0.200
LDL cholesterol†	Per 10 mg/dL	-0.007	0.010	0.47	-0.063
HDL cholesterol†	Per 10 mg/dL	0.008	0.025	0.74	0.021
CAD	(+) vs. (−)	-0.006	0.083	0.94	-0.008
Hypertension	(+) vs. (−)	0.143	0.084	0.09	0.195
Ever-smoking	(+) vs. (−)	-0.052	0.071	0.47	-0.072
Achilles tendon thickness (n = 64)
Sex	Male vs. female	-0.286	0.404	0.48	-0.091
Age	Per 10 years	-0.116	0.196	0.56	-0.094
LDL cholesterol†	Per 10 mg/dL	0.019	0.088	0.83	0.030
HDL cholesterol†	Per 10 mg/dL	0.047	0.220	0.83	0.029
CAD	(+) vs. (−)	0.293	0.556	0.60	0.088
Hypertension	(+) vs. (−)	0.414	0.555	0.46	0.109
Ever-smoking	(+) vs. (−)	0.391	0.468	0.41	0.112

^＊Regression coefficient divided by standard deviation of the parameter of study.

^†Change from baseline at 4 years of follow-up.