Fig.1. Indirect calorimetry during 24 hours (light and dark times) in LDL receptor knockout mice (LDLr^−/−) and treated with low doses of 2,4-dinitrophenol (LDLr^−/−DNP) .

Body O2 consumption (A), CO2 production (B) and energy expenditure (C) measurement each 2 hours during all day and an average during the light and dark time (n=7, ^＊p=0.023, ^#p=0.056).