Table 1. Baseline demographics and other characteristics (qualitative variables).
| Characteristic | PROSPECTIVE | IMPACT | PROSPECTIVE+IMPACT | |||||
|---|---|---|---|---|---|---|---|---|
| Control (N = 431) | Probucol (N = 400) | Control (N = 102) | Probucol (N = 92) | Control (N = 533) | Probucol (N = 492) | P value† | ||
| No. of patients (%) | No. of patients (%) | No. of patients (%) | ||||||
| Country | Japan | 431 (100.0) | 400 (100.0) | 0 (0.0) | 0 (0.0) | 431 (80.9) | 400 (81.3) | 0.986 |
| Korea | 0 (0.0) | 0 (0.0) | 48 (47.1) | 44 (47.8) | 48 (9.0) | 44 (8.9) | ||
| China | 0 (0.0) | 0 (0.0) | 54 (52.9) | 48 (52.2) | 54 (10.1) | 48 (9.8) | ||
| Sex | Male | 319 (74.0) | 291 (72.8) | 84 (82.4) | 78 (84.8) | 403 (75.6) | 369 (75.0) | 0.828 |
| Female | 112 (26.0) | 109 (27.3) | 18 (17.6) | 14 (15.2) | 130 (24.4) | 123 (25.0) | ||
| LDL-C | ＜140 mg/dL | 418 (97.0) | 388 (97.0) | 96 (94.1) | 86 (93.5) | 514 (96.4) | 474 (96.3) | 0.859 |
| ≥ 140 mg/dL | 13 (3.0) | 12 (3.0) | 3 (2.9) | 4 (4.3) | 16 (3.0) | 16 (3.3) | ||
| Diabetes mellitus | 181 (42.0) | 168 (42.0) | 42 (41.2) | 36 (39.1) | 223 (41.8) | 204 (41.5) | 0.949 | |
| Hypertension | 342 (79.4) | 325 (81.3) | 68 (66.7) | 63 (68.5) | 410 (76.9) | 388 (78.9) | 0.498 | |
| Peripheral artery disease | 14 (3.2) | 15 (3.8) | 1 (1.0) | 0 (0.0) | 15 (2.8) | 15 (3.0) | 0.855 | |
| Smoking status | Current smoker | 34 (7.9) | 15 (3.8) | 31 (30.4) | 27 (29.3) | 65 (12.2) | 42 (8.5) | 0.065 |
|
Nonsmoker (Ex-smoker/Never) |
396 (91.9) | 385 (96.3) | 71 (69.6) | 65 (70.7) | 467 (87.6) | 450 (91.5) | ||
| Coronary heart disease‡ | Myocardial infarction | 160 (37.1) | 138 (34.5) | 30 (29.4) | 24 (26.1) | 190 (35.6) | 162 (32.9) | 0.392 |
| Angina pectoris | 266 (61.7) | 258 (64.5) | 47 (46.1) | 43 (46.7) | 313 (58.7) | 301 (61.2) | 0.444 | |
| Cerebrovascular disease | 27 (6.3) | 25 (6.3) | 3 (2.9) | 8 (8.7) | 30 (5.6) | 33 (6.7) | 0.516 | |
†: Fisher’s exact test was used to evaluate the significance of differences between groups.
‡: Multiple choices were allowed.
LDL-C, low-density lipoprotein cholesterol