Table 2. Baseline demographics and other characteristics (quantitative variables).

Characteristic	PROSPECTIVE				IMPACT
	Control		Probucol		Control		Probucol
	N	mean±SD or median (IQR)	N	mean±SD or median (IQR)	N	mean±SD or median (IQR)	N	mean±SD or median (IQR)
Age (years)	431	70.0±9.4	400	70.0±9.0	102	63.5±6.8	92	64.1±7.1
Height (cm)	431	160.2±8.5	400	160.5±8.8	102	166.5±7.4	92	166.8±7.3
Weight (kg)	431	63.2±11.4	400	63.7±12.0	102	71.0±8.8	92	70.4±11.2
TC (mg/dL)	431	169.5±28.7	400	169.0±28.6	102	151.3±30.7	92	151.4±34.7
HDL-C (mg/dL)	431	54.4±14.4	400	53.6±13.6	102	46.6±12.4	92	46.4±11.8
LDL-C (mg/dL)	431	90.4±23.5	400	89.6±22.7	99	75.2±25.7	90	77.2±30.0
TG (mg/dL)	431	107 (80-154)	400	114 (83-158)	102	129 (92-185)	92	116 (83-165)
hs-CRP (ng/mL)	69	570 (216-1640)	56	698 (409-1585)	102	685 (300-1160)	92	665 (270-2145)
No. of cigarettes smoked on average daily (only current smokers)	34	20 (10-20)	15	10 (7-20)	31	10 (10-20)	27	10 (10-20)
Characteristic	PROSPECTIVE+IMPACT
	Control		Probucol		P value†
	N	mean±SD or median (IQR)	N	mean±SD or median (IQR)
Age (years)	533	68.7±9.3	492	68.9±9.0	0.965
Height (cm)	533	161.4±8.7	492	161.7±8.9	0.649
Weight (kg)	533	64.7±11.4	492	64.9±12.1	0.942
TC (mg/dL)	533	166.0±29.9	492	165.7±30.6	0.694
HDL-C (mg/dL)	533	52.9±14.4	492	52.3±13.6	0.588
LDL-C (mg/dL)	530	87.6±24.7	490	87.3±24.7	0.724
TG (mg/dL)	533	113 (83-157)	492	114 (83-158)	0.753
hs-CRP (ng/mL)	171	660 (254-1360)	148	669 (327-1720)	0.220
No. of cigarettes smoked on average daily (only current smokers)	65	15 (10-20)	42	10 (10-20)	0.196

^†: Two-sample Wilcoxon test was used to evaluate the significance of differences between groups.

^＊: The level of significance was set at p＜0.05 (2-sided).

hs-CRP, high-sensitivity C-reactive protein; HDL-C, high-density lipoprotein cholesterol; IQR, interquartile range; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglyceride