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. 2022 Feb 25;126(12):1795–1805. doi: 10.1038/s41416-022-01744-3

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Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — High expression includes strong positive and positive staining; Low expression includes weak positive and negative staining. Kaplan–Meier curve analysis of the relationship between Cathepsin F (CTSF) expression and progression-free survival after occurrence of non-small cell lung cancer (NSCLC) brain metastasis (BM) (a), survival after diagnosis of LCBM (b), overall survival from the time of diagnosis of NSCLC (c). LCBM = NSCLC BM patients.