Table 1.

Literature data for solubility of anti-cancer drugs in supercritical carbon dioxide.

CO2 (1) + drug (2)	Temperature (K)	Pressure (MPa)	CO2 density (kg/m3)	Drug solubility* × 106	No. data
Sorafenib tosylate19	308–338	12–27	388–914	0.68–12.57	24
Sunitinib malate20	308–338	12–27	388–914	5–85.6	24
Azathioprine21	308–338	12–27	388–914	2.7–18.3	24
Busulfan22	308–338	12–40	383–971	32.7–865	32
Tamoxifen23	308–338	12–40	383–971	18.8–989	32
Letrozole24	318–348	12–36	319–922	1.6–85.1	20
Tamsulosin25	308–338	12–27	384–914	0.18–10.13	24
Capecitabine26	308–348	15.2–35.4	477–955	2.7–158.8	40
Paclitaxel27	308–328	10–27.5	654–915	1.2–6.2	21
5-Fluorouracil27	308–328	12.5–25	541–901	3.8–14.6	18
Thymidine27	308–328	10–30	325–928	1.2–8	25
Decitabine28	308–338	12–40	383–971	28.4–1070	32