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. 2022 Jun 7;12:9370. doi: 10.1038/s41598-022-13338-3

Table 3.

In vitro cytotoxicity activities of betulin against different human cell lines.

Compound Concentration A-549 (Lung) DU-145 (Prostate) PC-3 (Prostate) IGROV-1 (Ovary) MCF-7 (Breast)
Betulin 1 µM 29 27 14 38 51
10 µM 78 86 64 81 89
100 µM 84 91 86 89 92
Adriamycin 1 × 10–5 M 84 69 80 81 79
5-FU 2 × 10–5 M 65 11 13 95 86