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msh-5(ea36) is impaired in crossover formation. Shown are the numbers of DAPI+ bodies in diakinesis oocytes for the respective genotypes. Control dpy-1 animals had only the expected 6 DAPI+ bodies. msh-5 heterozygous worms similarly had predominantly 6 DAPI bodies, whereas the msh-5(me23) null worms had 12 univalents in almost all nuclei. msh-5(ea36) mutant animals have increased numbers of univalents and chromosome fusions.
