Fig. 1.
Pancreatic β-cell glycolysis and metabolic pathways stemming from glycolysis. Arrow width represents the relative amount of metabolic flux mediated by each enzyme. The TCA cycle initiated by pyruvate entry, the glycerolipid/free fatty acid cycle boosted by glycerol-3-phosphate and the pentose phosphate pathway originating from glucose-6-phoshtae, mediate generation of metabolism-secretion coupling factors