Table 1.
Prevalence of diabetic retinopathy (DR) in acromegaly associated with diabetes mellitus (DM) or diabetes mellitus + impaired glucose tolerance (DM + IGT)
| References | Acromegaly (n) Total (DM/IGT/NGT) |
DR (n) Total (PDR/NPDR) |
DR (%) in DM/DM + IGT |
Macular abn n (%) |
|---|---|---|---|---|
| Amemiya et al. [2] | 15 (10/0/5) | 3 (0/3) | 30.0%/30.0% | n.d |
| Ballintine et al. [3] | 44 (6/20/18) | 1 (0/1) | 16.7%/3.8% | n.d |
| Azzoug et al. [4] | 40 (40/–/–) | 5 (2/3) | 12.5%/– | n.d |
| Wu et al. [5] | 43 (16/11/16) | 4 (4/0) | 18.8%/14.8% | n.d |
| Fuchtbauer et al. [6] | G 26 (7/6/13) | 3 (0/3) | 42.9%/23.1% | 2 (7.7%) |
| R 39 (39/–/–) | 5 (3/2) | 12.8%/– | 2 (5.1%) | |
| G + R 65 (46/6/13) | 8 (3/5) | 17.4%/15.4% | 4 (6.2%) |
abn abnormalities, DM diabetes mellitus, G Gothenberg cohort, IGT impaired glucose tolerance, n.d. not determined, NGT normal glucose tolerance, NPDR non-proliferative diabetic retinopathy, PDR proliferative diabetic retinopathy, R Rotterdam cohort