Table 3.
Blastocyst morphology-stratified analysis of blastocyst-transfer outcomes
| Outcome | Excellent-quality blastocysts | Good-quality blastocysts | Poor-quality blastocysts | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Control | GM-CSF |
P (OR [95% CI]) |
Control | GM-CSF |
P (OR [95% CI]) |
Control | GM-CSF |
P (OR [95% CI]) |
|
| No. of blastocyst transfers | 102 | 102 | — | 61 | 61 | — | 40 | 40 | — |
| Positive hCG result (%) | 63 (61.8) | 74 (72.6) |
0.101 (1.63 [0.91–2.95]) |
25 (41.0) | 36 (59.0) |
0.0464 (2.07 [1.01–4.27]) |
7 (17.5) | 22 (55.0) |
0.0005 (5.76 [2.06–16.1]) |
| Clinical pregnancy (%) | 57 (55.9) | 65 (63.7) |
0.1598 (1.39 [0.79–2.43]) |
22 (36.1) | 31 (50.8) |
0.1002 (1.83 [0.89–3.78]) |
4 (10.0) | 19 (47.5) |
0.0002 (8.14 [2.44–27.2]) |
| Ongoing pregnancy, week 22 (%) | 44 (43.14) | 57 (55.9) |
0.0687 (1.67 [0.96–3.24]) |
15 (24.6) | 22 (36.1) |
0.1680 (1.73 [0.79–3.78]) |
3 (7.50) | 12 (30.0) |
0.0099 (5.29 [1.36–20.5]) |
| Live birth (%) | 44 (43.14) | 57 (55.9) |
0.0687 (1.67 [0.96–3.24]) |
15 (24.6) | 22 (36.1) |
0.1680 (1.73 [0.79–3.78]) |
3 (7.50) | 12 (30.0) |
0.0099 (5.29 [1.36–20.5]) |
P values in bold typeface indicate statistical significance
aPercentage of the number of patients with clinical pregnancy
GM-CSF, granulocyte–macrophage colony-stimulating factor; OR, odds ratio; CI, confidence interval; hCG, human chorionic gonadotropin