Figure 6.

Glucose uptake is increased in LVS-infected PMNs and is required for apoptosis delay. (A) [³H]2-deoxy-D-glucose uptake was measured at 12 hr. *p < 0.05, n=6. (B, C) Apoptosis of control and LVS-infected PMNs in the presence or absence of WZB-117 measured by Annexin V-FITC staining and flow cytometry at the indicated timepoints (B) and at 24 h (C). *p < 0.05, ***p < 0.001, ****p < 0.0001 compared to untreated, control PMNs, ^‡‡‡‡ p < 0.0001 compared to untreated, LVS-infected PMNs as indicated, n=4.