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. 2022 Jun 7;12:9400. doi: 10.1038/s41598-022-13488-4

Table 1.

List of 5 most expressed genes across the menstrual cycle.

Menstrual Early proliferative Mid proliferative Late proliferative Early secretory Mid secretory Late secretory
PLCG1 PLCG1 PLCG1 PLCB1 PLCB1 PLCL1 PLCG1
COX-2 MAGL PLCB1 PLCG1 PLCL1 PLCB4 PLCB4
PLD1 PLCB1 MAGL MAGL MAGL MAGL MAGL
GDE-1 GDE-1 GDE-1 GDE-1 PLA2G4A PLCG1 PLCL1
MAGL PLCE1 PLCE1 PLA2G4A PLCG1 PLCB1 PLA2G7

5 highly expressed genes for each of the 7 menstrual stages with the most expressed gene at the top. The majority of the genes listed encode for synthesising enzymes of the endocannabinoid system with two exceptions of COX-2 and MAGL which encode for degrading enzymes.