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. 2022 Feb 11;126(12):1744–1754. doi: 10.1038/s41416-022-01719-4

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — This flow chart shows the total number of patients identified who underwent a lower gastrointestinal endoscopy along with the relevant exclusions made to arrive at the number of patients included for analysis and the number of accrued colorectal cancer cases. ^a conditions reported are not mutually exclusive. ^b a colonoscopy is considered complete if the colonoscope has reached the caecum. ^c proximal colon cancer incidence is defined as cancer located between the caecum and splenic flexure, International Classification of Diseases for Oncology, third edition (ICD-O-3) codes C18.0–C18.5. ^d distal colorectal cancer is defined as cancer located between the descending colon and the anus, ICD-O-3 codes C18.6–C18.7; C19; C20; C21.