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. 2022 May 25;13:875788. doi: 10.3389/fimmu.2022.875788

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Copyright © 2022 Sapra, Shokeen, Porwal, Saini, Bhardwaj, Mathew, Mishra, Chattopadhyay, Dar, Verma and Srivastava

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BL modulates cytokine balance in Ovx mice. Osteoclastogenic cytokines were analyzed in serum samples of mice by ELISA. Anti-osteoclastogenic cytokines were analyzed in serum samples of mice by ELISA. The results were evaluated by using ANOVA with subsequent comparisons by Student’s t-test for paired or non-paired data, as appropriate. Values are expressed as mean ± SEM (n = 6), and similar results were obtained in two independent experiments. Statistical significance was defined as p ≤ 0.05, *p ≤ 0.05, **p < 0.01, ***p ≤ 0.001 with respect to the indicated mouse group.