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. 2022 May 25;12:854658. doi: 10.3389/fonc.2022.854658

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Copyright © 2022 Huang, Pu, Huang, Yang, Yang, Pu, Li, Chen and Huang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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One patient with non–small cell lung cancer who developed systemic metastasis. (A) Maximum intensity projections at 10 min, 1 h, and 3 h after injection of ¹⁸F-FAPI-74 PET. (B) The uptake of ¹⁸F-FAPI-74 was significantly different between tumor and normal myocardium. (C) FAPI-positive lesions were confirmed on CT examination. (D, E) Some bone metastases were detected only by FAPI PET. All highlighted arrows represent FAPI uptake in relation to morphology (20).