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. 2022 May 25;13:872652. doi: 10.3389/fimmu.2022.872652

Figure 1.

Figure 1

Immune training increases overall metabolic rate of monocytes across all age groups. (A) Ex vivo trained immunity protocol. (B) Baseline and stressed oxygen consumption rate (OCR) 7 days after β–glucan or PBS treatment. (C) Baseline extracellular acidification rate (ECAR) and stressed ECAR 7 days after β–glucan or PBS treatment. Mixed effect model and Šídák’s multiple comparisons test (*P ≤ 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001) were used to compare (B, C) (N=13). ns, not significant.