Figure 4.

Immune training differentially stimulates monocyte histone modifications. (A) H3K4 methylation measured in situ 7 days after immune training with β–glucan or baseline control (N=5). (B) Histone H3K27 methylation 7 days after immune training with β–glucan or baseline control (N=6). All measured were analyzed with a mixed effect model and Šídák’s multiple comparisons test (*P ≤ 0.05, **P ≤ 0.01, ns, not significant).