Table 1.
Immune cell phenotypes.
| Phenotype | Cell Type | Primary (%) | Recurrence (%) | Brain Mets (%) |
|---|---|---|---|---|
| PD-1+ | B cell | 0.0 | 1.9 | 4.9 |
| CD4 T cells | 0.3 | 0.6 | 0.3 | |
| CD8 T cells | 0.8 | 1.9 | 3.6 | |
| Macrophages | 0.1 | 0.2 | 0.3 | |
| Other CD45+ cells | 0.7 | 0.2 | 0.2 | |
| Tregs (FOXP3+) | CD4 T cells | 0.2 | 0.4 | 0.5 |
| Ki67+ | B cell | 3.5 | 2.0 | 6.7 |
| CD4 T cells | 2.3 | 2.9 | 2.3 | |
| CD8 T cells | 2.1 | 3.1 | 6.2 | |
| Macrophages | 1.6 | 2.5 | 2.2 | |
| Other CD45+ cells | 3.1 | 4.2 | 2.0 | |
| CD44-High | CD4 T cells | 84.3 | 40.7 | 32.5 |
| CD8 T cells | 63.4 | 44.7 | 27.5 | |
| HLA-DR-High | B cell | 6.0 | 21.0 | 36.8 |
| CD4 T cells | 9.7 | 26.4 | 38.5 | |
| CD8 T cells | 6.6 | 8.1 | 23.8 | |
| Macrophages | 23.8 | 54.6 | 58.4 | |
| Other CD45+ cells | 4.2 | 9.8 | 23.9 | |
| Sting-High | B cell | 31.0 | 34.3 | 38.0 |
| CD4 T cells | 11.5 | 14.6 | 54.3 | |
| CD8 T cells | 17.8 | 28.9 | 52.0 | |
| Macrophages | 7.6 | 17.3 | 26.5 | |
| Other CD45+ cells | 22.9 | 30.5 | 61.4 |
The full name of each protein can be found in Supplementary Table S1 .