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. 2022 May 25;13:883073. doi: 10.3389/fgene.2022.883073

TABLE 3.

Characteristics of MyCode participants and general Geisinger population.

MyCode participants who consented or re-consented after 2013 (N = 2,15,078) MyCode participants who declined or withdrew or have not reconsented after 2013 (N = 1,00,314) p-value a General Geisinger population (N = 20,72,639) p-value b
Age, median [IQR] 55 [38, 68] 57 [39, 71] p < 2.2 × 10−16 40 [20, 62] p < 2.2 × 10−16
Sex, n (%)
 Female 1,28,149 (59.6) 60,456 (60.3) p < 0.0001 10,79,082 (52.1) p < 2.2 × 10−16
 Male 86,928 (40.4) 39,850 (39.7) 9,93,557 (47.9)
 Unknown 1 (0.0) 8 (0.0)
Race, n (%)
 White/European ancestry 2,06,102 (95.8) 94,487 (94.2) p < 2.2 × 10−16 18,76,010 (90.5) p < 2.2 × 10−16
 Black/African ancestry 5,771 (2.7) 3,795 (3.8) 1,09,164 (5.3)
 Native American 278 (0.1) 132 (0.1) 2,995 (0.1)
 Asian or Pacific Islander 1,516 (0.7) 1,515 (1.5) 36,894 (1.8)
 Unknown/other 1,411 (0.7) 385 (0.4) 47,576 (2.3)
Ethnicity, n (%)
 Hispanic/Latinx 6,284 (2.9) 3,572 (3.6) p < 2.2 × 10−16 1,07,788 (5.2) p < 2.2 × 10−16
 Not Hispanic/Latinx 2,06,776 (96.1) 94,725 (94.4)
 Unknown 2018 (0.9) 2017 (2.0)
 Have a Geisinger PCP, n (%) 1,32,652 (61.7) 60,428 (60.2) p < 0.0001 5,94,847 (28.7) p < 2.2 × 10−16
 Insured with GHP, n (%) 82,926 (38.6) 34,240 (34.1) p < 2.2 × 10−16 4,51,835 (21.8) p < 2.2 × 10−16
 CCI, median [IQR] 2 [0, 4] 2 [0, 4] p < 2.2 × 10−16 0 p < 2.2 × 10−16

PCP, primary care provider; GHP, Geisinger health plan; CCI, Charlson comorbidity index; IQR, interquartile range.

a

Comparison between MyCode screening population and control population. Chi-squared test was performed for categorical variables with multiple levels (Sex, Race, and Ethnicity). Z-test for two proportions was used for categorical variables with two levels (%Geisinger PCP, %GHP). Two-sample Wilcoxon test was used for comparing the medians for continuous variables (Age and CCI).

b

Comparison between MyCode screening population and Geisinger population. Chi-squared test was performed for categorical variables with multiple levels (Sex and Race). Z-test for one proportion was used for logistical variables or categorical variables with two levels (Sex, % Hispanic/Latinx, %Geisinger PCP, %GHP). One-sample Wilcoxon test was used for non-normal continuous variables (Age and CCI), treating the medians of the general Geisinger population as the population median.