Table 3.
Correlation between PDHA complex components and androgen receptor protein expression in prostate cancer.
| Patients - no. | N = 120 | AR negative | AR positive |
|---|---|---|---|
| (N = 26) | (N = 92) | ||
| Missing | 2 | ||
| PDHA1- no. (%) | p = 0.195 / P = 0.035 | ||
| Negative | 89 (75) | 23 (88) | 66 (72) |
| Positive | 28 (24) | 2 (8) | 26 (28) |
| Missing | 1 (1) | 1 (4) | 0 (0) |
| PDP1 - no. (%) | p = 0.184 / P = 0.046 | ||
| Negative | 104 (88) | 25 (96) | 79 (86) |
| Positive | 13 (11) | 0 (0) | 13 (14) |
| Missing | 1 (1) | 1 (4) | 0 (0) |
| PDP2 - no. (%) | p = 0.124 / P = 0.180 | ||
| Negative | 86 (73) | 21 (80) | 65 (70) |
| Positive | 31 (26) | 4 (15) | 27 (30) |
| Missing | 1 (1) | 1 (4) | 0 (0) |
| PDK1 - no. (%) | p = 0.282 / P = 0.003 | ||
| Negative | 26 (22) | 11 (42) | 15 (16) |
| Positive | 87 (74) | 13 (50) | 74 (81) |
| Missing | 5 (4) | 2 (8) | 3 (3) |
| PDK2 - no. (%) | p = 0.299 / P = 0.001 | ||
| Negative | 15 (13) | 8 (30) | 7 (7) |
| Positive | 102 (86) | 17 (65) | 85 (93) |
| Missing | 1 (1) | 1 (4) | 0 (0) |
| PDK3 - no. (%) | p = -0.046 / P = 0.625 | ||
| Negative | 13 (11) | 2 (8) | 11 (12) |
| Positive | 99 (84) | 21 (80) | 78 (85) |
| Missing | 6 (5) | 3 (12) | 3 (3) |
| PDK4 - no. (%) | p = 0.206 / P = 0.031 | ||
| Negative | 14 (12) | 6 (23) | 8 (9) |
| Positive | 96 (81) | 17 (65) | 79 (86) |
| Missing | 8 (7) | 3 (12) | 5 (5) |
Spearsman's correlation p (95% Cl) / P value; AR, Androgen receptor.