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. 2022 Apr 7;3(6):e408–e416. doi: 10.1016/S2666-5247(21)00308-6

Table 3.

Stool myeloperoxidase and α1-antitrypsin concentrations

All participants (n=43) Gastro-intestinal*symptoms (n=31) No gastro-ntestinal symptoms (n=12) p-value
Myeloperoxidase
Concentration, ng/mL 1574 (597–3806) 2225 (812–4033) 663 (295–2335) 0·088
Number elevated 19 (44%) 16 (52%) 3 (25%) 0·11
α1-antitrypsin
Concentration, μg/mL 217 (146–438) 257 (142–475) 211 (186–261) 0·80
Number elevated§ 15 (35%) 13 (42%) 2 (17%) 0·12
Total number of elevated myeloperoxidase or α1-antitrypsin 23 (53%) 19 (61%) 4 (33%) 0·10

Data are n (%) or median (IQR) unless otherwise specified.

*

Gastrointestinal symptoms of diarrhoea or abdominal pain.

Comparisons between results in those with gastrointestinal symptoms and those without gastrointestinal symptoms were calculated by Mann-Whitney U test for continuous variables and by Fisher's exact test for categorical variables.

Defined as myeloperoxidase >2000 ng/mL.

§

Defined as α1-antitrypsin >270 μg/mL.