Table 1.
Top 10 aging-correlated genes in the thyroid gland.
| Gene | Description | TCGA THCA | GTEx | ||
|---|---|---|---|---|---|
| Rho | FDR | Rho | FDR | ||
| PTCHD4 | Patched domain containing 4 | 0.5424 | 0.0180 | 0.4718 | 4.54E-30 |
| SPATA18 | Spermatogenesis associated 18 | 0.4978 | 0.0607 | 0.3932 | 1.66E-19 |
| POU3F4 | POU class 3 homeobox 4 | 0.6037 | 0.0031 | 0.3197 | 1.09E-12 |
| BMPR1B | Bone morphogenetic protein receptor type 1B | 0.6019 | 0.0031 | 0.2919 | 1.25E-10 |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 | 0.5530 | 0.0137 | 0.3081 | 8.39E-12 |
| RPS27L | Ribosomal protein S27 like | 0.5048 | 0.0501 | 0.2885 | 2.19E-10 |
| DAPL1 | Death associated protein like 1 | 0.5550 | 0.0130 | 0.2626 | 1.00E-08 |
| SMCO3 | Single-pass membrane protein with coiled-coil domains 3 | 0.5567 | 0.0136 | 0.2525 | 4.09E-08 |
| TAFA3 | TAFA chemokine like family member 3 | 0.5325 | 0.0234 | 0.2604 | 1.38E-08 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor | 0.4680 | 0.0907 | 0.2800 | 7.53E-10 |
FDR, Benjamini-Hochberg false discovery rate; Rho, Spearman rank-order correlation coefficient.