Table 2.
Prevalence of herpesvirus reactivation, viral load, and correlation of herpesvirus reactivation with the SARS-CoV-2 load
| Virus | Prevalence n (%) | SARS-CoV-2 load (mean ± DP) | Kendall’s Tau-b Correlation coefficient (coefficient; p value) |
|---|---|---|---|
| HSV-1 | 9/53 (17) | 3.54E+9 ± 1.0E+10 | 0.556; p = 0.037* |
| HSV-2 | 1/53 (1.9) | 1930 | – |
| EBV | 15/53 (28.3) | 1.52E+12 ± 3.99E+12 | − 0.162; p = 0.400 |
| CMV | 23/53 (43.4) | 1.31E+11 ± 3.28E+11 | 0.020; p = 0.895 |
| VZV | 4/53 (7.5) | 1.32E+10 ± 2.26E+10 | – |
| HHV-6 | 25/53 (47.2) | 8.52E+11 ± 2.14E+12 | − 0.223; p = 0.102 |
| HHV-7 | 21/53 (39.6) | 2.83E+11 ± 6.57E+11 | 0.181; p = 0.251 |
| HHV-8 | 9/53 (17) | 9.50E+5 ± 2.40E+6 | 0,355; p = 0.139 |
aKendall’s Tau-b coefficient indicates the association of the SARS-CoV-2 load with the load viral of each herpesvirus. Missing values indicate that the test could not be conducted owing to a small sample size
SARS-CoV-2 severe acute respiratory syndrome coronavirus 2, HSV herpes simplex virus, VZV varicella zoster virus, EBV Epstein–Barr virus, CMV cytomegalovirus, HHV human herpesvirus
*Statistical significance