TABLE 7.

Multivariate linear mixed models of CI over time.

	Regression coefficient (95%CI)	p-value
Visit	64.77 (from 57.67 to 71.87)	0.000
BMI, Kg/m2	−7.27 (from −13.78 to −0.76)	0.029
HOMA, (mmol/L*[μU/ml]/22.5)	−6.33 (from −10.12 to −2.53)	0.001
e-GFR, ml/min/1.73 m2	0.63 (from −0.25 to 1.51)	0.161
Uric acid, mg/dl	−12.75 (from −28.04 to 2.53)	0.102
IGF-1, ng/ml	0.98 (from 0.34 to 1.62)	0.003
HbA1c, %	−3.34 (from −19.98 to 13.29)	0.694

BMI, body mass index; HOMA, homeostatic model assessment; e-GFR, estimated glomerular filtration rate; IGF-1, insulin-like growth factor-1; HbA1c, glycated haemoglobin.

The dependent variables that significantly correlate with the dependent variable of each Multivariate linear mixed models are shown in bold.