Table 3.

Baseline characteristics of hypothetical individuals with T2D

	Patient A	Patient B	Patient C
Age, years	60	70	75
Sex	Male	Female	Male
Diabetes duration, years	10	12	18
Current smoker	No	Yes	No
BMI, kg/m2	33	28	30
HbA1c, mmol/mol	52	48	56
SBP, mmHg	137	125	140
Non-HDL cholesterol, mmol/L	3	2.5	3.5
eGFR, mL/min/1.73 m2*	75	70	82
Microalbumin	No	Yes	No
Macroalbumin	No	No	No
History of CVD	Yes	No	Yes
Use of insulin	No	No	Yes
10-year CVD risk, %	25.4	2.9	53.2
10-year CVD risk with the addition of semaglutide to SoC, %	19.9	2.2	44.2

eGFR, estimated glomerular filtration rate; SBP, systolic blood pressure.

^*Estimated using the CKD-EPI creatinine equation.