Figure 6.

ILK expression is correlated with Tregs and M2 macrophages infiltration and their gene markers in COAD, LUSC and STAD. (A, C, E, G) ILK expression correlation with Tregs and M2 macrophages infiltration in COAD, KIRC, LUSC and STAD via TIMER platform. (B, D, F, H) Gene markers for M2 macrophage (CD163), Treg cells (FOXP3) and their correlation with ILK in COAD, KIRC, STAD and LUSC via GEPIA. QUANTISEQ and CIBERSORT-ABB are different methods used via TIMER for cell quantification based on gene expression. Since most immune cells are negatively correlated with tumor purity, the correlation is adjusted by purity partial spearman’s correlation rho. R is Spearman’s correlation Rho value. The significant P-value is <0.05.