Table 3.
Gene markers | COAD | KIRC | STAD | LUSC | |||||
R | P | R | P | R | P | R | P | ||
Monocyte | CD86 | 0.56 | *** | 0.11 | ** | 0.37 | *** | 0.47 | *** |
CSF1R | 0.59 | *** | 0.27 | *** | 0.51 | *** | 0.53 | *** | |
TAM | CCL2 | 0.59 | *** | 0.36 | *** | 0.43 | *** | 0.49 | *** |
CD68 | 0.51 | *** | 0.1 | * | 0.28 | *** | 0.44 | *** | |
IL10 | 0.52 | *** | 0.15 | ** | 0.41 | *** | 0.43 | *** | |
M2 Macrophage | CD163 | 0.56 | *** | 0.04 | 0.27 | 0.43 | *** | 0.45 | *** |
VSIG4 | 0.6 | *** | 0.12 | * | 0.52 | *** | 0.47 | *** | |
MS4A4A | 0.57 | *** | 0.15 | ** | 0.48 | *** | 0.46 | *** | |
Dendritic cell | HLA-DPB1 | 0.5 | *** | 0.24 | *** | 0.31 | *** | 0.48 | *** |
HLA-DQB1 | 0.23 | *** | 0.15 | ** | 0.1 | * | 0.3 | *** | |
HLA-DRA | 0.41 | *** | 0.19 | *** | 0.25 | *** | 0.47 | *** | |
HLA-DPA1 | 0.47 | *** | 0.21 | *** | 0.29 | *** | 0.48 | *** | |
CD1C | 0.43 | *** | 0.33 | *** | 0.36 | *** | 0.28 | *** | |
NRP1 | 0.66 | *** | 0.59 | *** | 0.55 | *** | 0.51 | *** | |
ITGAX | 0.54 | *** | 0.02 | 0.52 | 0.37 | *** | 0.35 | *** | |
Neutrophils | CEACAM8 | -0.07 | 0.21 | 0.08 | 0.055 | 0 | 0.94 | 0.14 | * |
ITGAM | 0.61 | *** | 0.22 | *** | 0.43 | *** | 0.44 | *** | |
CCR7 | 0.4 | *** | 0.14 | * | 0.33 | *** | 0.26 | *** | |
Treg | FOXP3 | 0.46 | *** | -0.06 | 0.15 | 0.23 | *** | 0.38 | *** |
CCR8 | 0.48 | *** | 0.02 | 0.65 | 0.36 | *** | 0.38 | *** | |
STAT5B | 0.34 | *** | 0.62 | *** | 0.55 | *** | 0.07 | 0.12 | |
TGFB1 | 0.63 | *** | 0.28 | *** | 0.58 | *** | 0.35 | *** | |
T cell exhaustion | PDCD1 | 0.34 | *** | -0.02 | 0.65 | 0.24 | *** | 0.22 | *** |
CTLA4 | 0.39 | *** | 0.03 | 0.42 | 0.16 | ** | 0.28 | *** | |
LAG3 | 0.29 | *** | -0.04 | 0.32 | 0.16 | * | 0.12 | * | |
HAVCR2 | 0.59 | *** | 0.13 | * | 0.42 | *** | 0.46 | *** | |
GZMB | 0.18 | * | 0.16 | ** | 0.1 | * | 0.12 | * |
Correlations of ILK with gene markers expression in tumor tissues from TCGA analyzed via GEPIA. R is Spearman’s correlation Rho value. The significant P-value is <0.05. *P < 0.05, **P < 0.01, ***P < 0.001.