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. 2022 May 25;14:819499. doi: 10.3389/fnagi.2022.819499

TABLE 3.

Association of SNPs of candidate genes and odds ratio to AD risk.

Gene SNP Minor allele Allele model Dominant model (Adjusted) Recessive model (Adjusted) Additive model (Adjusted)




P-value OR 95% CI P-value OR 95% CI P-value OR 95% CI P-value OR 95% CI
ABCA7 rs3764650 G 0.010 1.43 1.09–1.89 0.004 1.71 1.19–2.46 0.419 1.27 0.71–2.26 0.012 1.42 1.08–1.86
ABCA7 rs4147929 A 0.006 1.45 1.11–1.89 0.012 1.59 1.11–2.27 0.101 1.54 0.92–2.59 0.010 1.40 1.08–1.81

AD, Alzheimer’s Disease; CI, confidence interval; OR, odds ratio; SNP, single nucleotide polymorphism. P allele was examined using the Chi-square test. P-value was adjusted for age and gender with logistic regression. Bold indicates statistically significant values.