TABLE 3.
Association of SNPs of candidate genes and odds ratio to AD risk.
| Gene | SNP | Minor allele | Allele model | Dominant model (Adjusted) | Recessive model (Adjusted) | Additive model (Adjusted) | ||||||||
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| P-value | OR | 95% CI | P-value | OR | 95% CI | P-value | OR | 95% CI | P-value | OR | 95% CI | |||
| ABCA7 | rs3764650 | G | 0.010 | 1.43 | 1.09–1.89 | 0.004 | 1.71 | 1.19–2.46 | 0.419 | 1.27 | 0.71–2.26 | 0.012 | 1.42 | 1.08–1.86 |
| ABCA7 | rs4147929 | A | 0.006 | 1.45 | 1.11–1.89 | 0.012 | 1.59 | 1.11–2.27 | 0.101 | 1.54 | 0.92–2.59 | 0.010 | 1.40 | 1.08–1.81 |
AD, Alzheimer’s Disease; CI, confidence interval; OR, odds ratio; SNP, single nucleotide polymorphism. P allele was examined using the Chi-square test. P-value was adjusted for age and gender with logistic regression. Bold indicates statistically significant values.