Table 4.

Risk of Bias measures for experimental studies.

Item	Description
1.1	Was the allocation sequence random?
1.3	Did baseline differences between intervention groups suggest a problem with the randomization process?
2.6	Was an appropriate analysis used to estimate the effect of assignment to intervention?
2.7	Was there potential for a substantial impact (on the result) of the failure to analyze participants in the group to which they were randomized?
5.1	Were the data that produced this result [the results for this study] analyzed in accordance with a pre‐specified analysis plan that was finalized before unblinded outcome data were available for analysis?
5.2	Is (Are) the numerical result [results] being assessed likely to have been selected, on the basis of the results, from multiple outcome measurements?
5.3	Is (Are) the numerical result [results] being assessed likely to have been selected, on the basis of the results, from multiple analyses of the data?