Table 1. Characteristics of Hospitals and Patients With Stroke Who Underwent Endovascular Thrombectomy.
| Variable | Age, y, No. (%) | Standardized difference | |
|---|---|---|---|
| <80 (n = 29 654) | 80 and over (n = 12 768) | ||
| Patient characteristics | |||
| Age, median (IQR) [range], y | 65 (56-73) [18-79] | 85 (82-89) [80-105] | 322.1a |
| Sex | |||
| Women | 13 203 (44.5) | 8431 (66.0) | 44.3a |
| Men | 16 451 (55.5) | 4337 (34.0) | |
| Race and ethnicity | |||
| Asian | 944 (3.2) | 1342 (3.2) | 31.3a |
| Black, non-Hispanic | 5213 (17.6) | 1001 (7.8) | |
| Hispanic (any race) | 2121 (7.2) | 766 (6.0) | |
| White, non-Hispanic | 19 540 (65.9) | 9889 (77.5) | |
| Otherb | 1836 (6.2) | 714 (5.6) | |
| Patient location at onsetc | |||
| None | 27 558 (93.7) | 11 101 (87.6) | 30a |
| Another acute care facility | 1074 (3.7) | 420 (3.3) | |
| Chronic health care facility | 508 (1.7) | 1034 (8.2) | |
| Outpatient health care setting | 266 (0.9) | 118 (0.9) | |
| Arrival by EMS | 16 372 (55.3) | 7742 (60.7) | 11.1 |
| Onset to arrival time, min | 134 (58-217) | 122 (54-210) | 6.5 |
| NIHSS initial score, median (IQR) | 17 (12-22) | 19 (14-23) | 24.4 |
| Ambulation status before admissiond | |||
| Independent | 21 733 (96.5) | 8460 (90.7) | 14.7 |
| With assistance (from person) | 444 (2.0) | 583 (6.3) | |
| Unable to ambulate | 346 (1.5) | 281 (3.0) | |
| Intravenous tPA use | |||
| At EVT hospital | 12 059 (40.7) | 4940 (38.5) | 4.6 |
| At another hospital | 7984 (39.4) | 2747 (32.4) | 14.7 |
| Medical history | |||
| Atrial fibrillation/flutter | 7958 (26.8) | 7108 (55.7) | 61.3a |
| Coronary artery disease or myocardial infarction | 6534 (22.0) | 3600 (28.2) | 14.2 |
| Diabetes | 7636 (25.8) | 2920 (22.9) | 6.7 |
| Dyslipidemia | 11 699 (39.5) | 6180 (48.4) | 18.1 |
| Hypertension | 19 857 (67.0) | 10 253 (80.3) | 30.6a |
| Chronic kidney disease | 1599 (5.4) | 1188 (9.3) | NA |
| Smoker | 6604 (22.3) | 379 (3.0) | 60.7a |
| Prior stroke/TIA | 5891 (19.9) | 3187 (25.0) | 12.2 |
| Medications before admission | |||
| Anticoagulant use | 4889 (22.5) | 3117 (37.8) | 33.8a |
| Antiplatelet use | 10 081 (38.1) | 5747 (54.1) | 32.5a |
| Physiologic measurements | |||
| Systolic blood pressure, median (IQR), mm Hg | 146 (129-165) | 153 (136-173) | NA |
| BMI | 29 | 26 | 55.3a |
| Hospital characteristics | |||
| Academic | 27 302 (92.1) | 11 546 (90.4) | 5.8 |
| Stroke center status | 7.3 | ||
| Comprehensive stroke center | 12 828 (43.3) | 5065 (39.7) | NA |
| Primary stroke center | 12 892 (43.5) | 5864 (45.9) | |
| Neither | 3934 (13.3) | 1839 (14.4) | |
| Annual volume, median (IQR) | |||
| Ischemic stroke | 390 (280-528) | 379 (274-527) | 2.0 |
| EVT | 77 (48-117) | 76 (48-116) | NA |
| Regione | 11.5 | ||
| Northeast | 5910 (19.9) | 2977 (23.3) | NA |
| Midwest | 6236 (21.0) | 2615 (20.2) | |
| South | 12 080 (40.7) | 4599 (36.0) | |
| West | 5427 (18.3) | 2577 (20.2) | |
Abbreviations: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); EVT, endovascular thrombectomy; NA, not applicable; TIA, transient ischemic attack; tPA, tissue plasminogen activator.
a
Clinically meaningful difference.
b
American Indian/Alaska Native, Native Hawaiian/Pacific Islander, or unable to determine.
c
The denominator for number and percentage values is 29 406 patients for age less than 80 years and 12 673 patients for age 80 and older.
d
The denominator for number and percentage values is 22 523 patients for age less than 80 years and 9324 patients for age 80 and older.
e
The denominator for number and percentage values is 29 653 patients for age less than 80 years.